Saxmeadham, including flanking walls, front boundary wall and gate piers

Saxmeadham is a neo-Georgian house built in 1911 to designs by architect Arnold Bidlake Mitchell. It faces east onto the road and is constructed of dark red brick laid in Flemish bond with lighter red brick and stone dressings, beneath a handmade plain tile roof of variegated brown and red with bonnet tiles.

The house has a rectangular double-pile plan with two storeys and an attic. A projection on the north gable end contains coal and wood storage. Reception rooms occupy the rear west pile overlooking the garden, while service rooms are located in the north part of the house.

The restrained neo-Georgian exterior relies on the textural quality of materials for effect. The front elevation is five bays wide beneath an M-shaped hipped roof with sprocketed eaves, the underside clad in timber. Two wide chimney stacks with moulded cornices rise from the roof valley, which also contains dormer windows lighting the attic. Fenestration consists of two-light casements with leaded lights set in moulded wooden frames with ovolo mullions. Between ground and first-floor windows are panels of roughly dressed coursed stone edged in light red brick. The central two-panelled front door has an ashlar stone bolection moulded surround with a pulvinated frieze and dentilled canopy. An oval nabrasena stone plaque on the left is inscribed 'SIR FREDERICK GOWLAND HOPKINS O.M F.R.S Pioneer Biochemist Nobel Laureate lived here 1911-1947'. A square Hoptonwood stone plaque on the right reads 'SAXMEADHAM seventy-one'.

The west garden elevation has canted bay windows in the second and fourth bays, each with dentilled cornice and French windows with leaded lights and two lower moulded panels, flanked by tall leaded windows. First-floor windows are positioned directly under the eaves. The north gable end has a window on the left; on the right is a single-storey hipped-roof projection sheltering the back door and containing the coal and wood store with original timber partition and original outdoor W.C. The south gable end has a first-floor window.

The interior is decorated in an elegant, restrained 18th-century style with moulded cornices, picture rails, skirting boards, and door frames throughout. Two-panelled doors are plain in service areas but fielded and panelled elsewhere, complete with lock cases and drop handles. Floors include parquet and wooden boards; windows have moulded wooden canopies and ornate ironmongery. The staircase hall, study, sitting room and dining room each contain delicate Classical fireplaces of painted timber with Art Nouveau and floral-design tiles predominantly in green and blue; some have been boarded over or fitted with gas fires but most grates survive. The dining room and drawing room connect via a double-leaf panelled door. The drawing room ceiling is embellished with a delicate raised plaster border in an intertwining Tudor rose design. The open well staircase has a panelled spandrel, closed string, turned balusters supporting a moulded handrail, and square newel posts descending below the string to form drop finials. Bedrooms have moulded picture rails, built-in cupboards, and simple painted timber fireplace surrounds, some boarded over but retaining grates.

The entrance hall and adjacent W.C. have black and white tiled floors. The W.C. retains its lavatory with square wooden seat, oval basin supported by ornate brackets, fitted towel rail, and a door lock displaying 'SHUT' or 'OPEN'. The first-floor W.C. also retains this door furniture. The attic bathroom contains a roll-top bath and original basin. Service rooms are similarly well-preserved: the kitchen retains the alcove and mantelshelf for the range, service hatch, built-in cupboards, service bell and indicator board. The scullery has a sink and fitted bench; the larder has a slate bench and shelves; what was probably the butler's pantry has a sink with wooden draining boards and built-in cupboards.

Curved flanking walls extend from the front corners of the house. The north side contains a plank and batten door under a round brick arch, providing garden access. A dwarf wall borders the front lawn, terminating at both ends in pairs of square brick piers with stone caps and ball finials.